Onc Now: Episode 3: Redefining Breast Cancer

This week, Jonathan Sackier is joined by Carlos Caldas, a world-leading expert in breast cancer research and clinician scientist at the University of Cambridge. Together, they explore how genomic-based classifications of breast cancer are transforming treatment strategies and improving patient outcomes.

Timestamps:
(00:00) – Introduction

(02:00) – Carlos’s favourite cuisine

(03:32) – Carlos’s journey into oncology

(08:30) – The redefinition of breast cancer

(14:30) – How this taxonomy influences clinical care

(20:15) - Patient-derived xenografts for breast cancer

(28:00) - Circulating plasma cell-free tumour DNA as a marker of tumour burden

(33:00) – Patient derived tumour cells for drug screening

(35:00) – Vitamin B5 and environmental factors in oncology

(38:44) – Current developments in breast cancer aetiology, diagnosis or treatment

(44:00) – The three wishes for the future of healthcare

(45:00) – Outro