S1 EP4: Treatment options in patients with heart failure across the spectrum of left ventricular ejection fraction with a particular interest in the pooling of previous results to gain greater insight

Episode 4 - Treatment options in patients with heart failure across the spectrum of left ventricular ejection fraction with a particular interest in the pooling of previous results to gain greater insight. - Dr. Milton Packer

We are joined by Dr. Milton Packer. He is a Distinguished Scholar in Cardiovascular Science at Baylor University Medical Center, Dallas in the United States. He is also a visiting professor at Imperial College London. He is one of the world leaders in the field of heart failure, has been a member of the FDA for over 30 years and founded the Heart Failure society of the America, He has published over 500 peer-reviewed articles, reviews, and editorials along with over 30 book chapters in the field.

For this episode, we will look at what further insights can be gained from pooling these results and hear the potential of empagliflozin as a treatment approach for patients right across the ejection fraction spectrum.

References:

Butler J, et al. Effect of empagliflozin in patients with heart failure across the spectrum of left ventricular ejection fraction. Eur Heart J. 2022;43(5):416-426. doi:10.1093/eurheartj/ehab798

Packer, M, et al. Design of a prospective patient-level pooled analysis of two parallel trials of empagliflozin in patients with established heart failure. Eur J Heart Fail, 22: 2393-2398. doi: 10.1002/ejhf.2065

Butler J, et al. Empagliflozin, Health Status, and Quality of Life in Patients With Heart Failure and Preserved Ejection Fraction: The EMPEROR-Preserved Trial. Circulation. 2022;145(3):184-193. doi:10.1161/CIRCULATIONAHA.121.057812

Butler J., et al. Early Benefit with Empagliflozin in Heart Failure with Preserved Ejection Fraction Insights from the EMPEROR-Preserved Trial. Eur J Heart Fail. 2022 Jan 5. doi: 10.1002/ejhf.2420

Ferreira JP, et al. Empagliflozin and serum potassium in heart failure: an analysis from EMPEROR-Pooled, Eur Heart J. 2022;43(31):2984-2993. doi:10.1093/eurheartj/ehac306  (there is a correction on this in relation to author affiliations, not the results).

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