An analysis of the IRIS® Registry shows IOL exchanges are increasing over time with vision improving 60% of the time, but worse visual outcomes associated with greater age, worse baseline vision, Black race, Hispanic ethnicity, Medicaid insurance, smoking, and concurrent vitrectomy. Dr. Matt Feng sits with authors Drs. David F. Chang and Fasika A. Woreta to discuss these findings and more from their Ophthalmology article, “Visual Acuity Outcomes and Complications after Intraocular Lens Exchange: An IRIS® Registry (Intelligent Research in Sight) Analysis.” Visual Acuity Outcomes and Complications after Intraocular Lens Exchange. Son, Hyeck-Soo et al. Ophthalmology, Volume 131, Issue 4, 403 – 411. The Ophthalmology-family of journals is now on Instagram. Follow aaojournal for clinical images, research articles, news, editorials, podcasts, and more!

The Department of Health and Human Services, Health Resources and Services Administration’s Health Workforce Simulation Model forecasts a sizeable shortage of ophthalmology supply relative to demand by the year 2035, with substantial geographic disparities. Dr. Edmund Tsui is here with author Dr. Sean T. Berkowitz to breakdown the implications of this shortage from his recent Ophthalmology article, Ophthalmology Workforce Projections in the United States, 2020 to 2035. Ophthalmology Workforce Projections in the United States, 2020 to 2035. Berkowitz, Sean T. et al. Ophthalmology, Volume 131, Issue 2, 133 – 139. The Ophthalmology-family of journals is now on Instagram. Follow aaojournal for clinical images, research articles, news, editorials, podcasts, and more!

Scleral buckling is a common surgical procedure for the repair of rhegmatogenous retinal detachment. The association between scleral buckling and angle-closure glaucoma is well-documented. However,the influence of scleral buckling on the development and progression of open-angle glaucoma is less well understood. Dr. Lori Provencher interviews Dr. Arthur J. Sit on the effect of scleral buckle surgery on ocular biomechanics and aqueous humor dynamics from his Ophthalmology Glaucoma article, “The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics.” The Effect of Scleral Buckle Surgery on Tonographic Outflow Facility, Positional Intraocular Pressure, and Ocular Biomechanics. Lyons, Lance J. et al. Ophthalmology Glaucoma, Volume 7, Issue 1, 1 – 7. The Ophthalmology-family of journals is now on Instagram. Follow @aaojournal for clinical images, research articles, news, editorials, podcasts, and more!

Neuro-ophthalmology consultations are critical to the diagnosis and management in the hospital setting. Prompt consultation prevents diagnostic errors and improves patient outcomes. The scarcity of neuro-ophthalmologists means that the increasing outpatient demand cannot be met, prompting many emergency department referrals by non–neuro-ophthalmologists. Dr. Drew Carey discusses this shortage of neuro-ophthalmologists and the need for technological and diagnostic aids for greater outpatient access with Dr. Valérie Biousse, author of “Neuro-ophthalmology Emergency Department and Inpatient Consultations at a Large Academic Referral Center.” Neuro-ophthalmology Emergency Department and Inpatient Consultations at a Large Academic Referral Center. Okrent Smolar, Avital Lily et al. Ophthalmology, Volume 130, Issue 12, 1304 – 1312

Syphilis is often known as the “the great masquerader” because it can mimic symptoms and look like a wide array of other diseases. Dr. Edmund Tsui interviews Dr. Michael Huvard to get to the bottom of how acute syphilitic posterior placoid chorioretinopathy presents itself in eyes and the outcomes for these patients, from his Ophthalmology article “Clinical Characteristics and Visual Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy” Clinical Characteristics and Visual Outcomes of Acute Syphilitic Posterior Placoid Chorioretinopathy. Mirzania, Delaram et al. Ophthalmology Retina, Volume 7, Issue 12, 1080 - 1086 Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Dr. Drew Carey sits down with Dr. Thomas V. Johnson to discuss the work of the RReSTORe Consortium in the field of regenerative medicine as applied to optic neuropathies from his Ophthalmology Science article, “The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, & Optic Nerve Regeneration (RReSTORe) Consortium.” For more of the Ophthalmology Science special issue on Neuroprotection, Neuroenhancement, and Neuroregeneration visit https://www.ophthalmologyscience.org/xops-vsi-neuroprotection For more information on the RReSTORe Consortium visit: https://www.johnsonlab.co/rrestore-home/rrestore-main-page/ The Retinal Ganglion Cell Repopulation, Stem Cell Transplantation, and Optic Nerve Regeneration Consortium. Johnson, Thomas V. et al. Ophthalmology Science, Volume 3, Issue 4. Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Endothelial keratoplasty (EK) procedures have become the preferred method of corneal transplantation in the United States. As the frequency of EKs increase, so do associated costs. Dr. Matt Feng interviews Drs. David S. Portney and Shahzad I. Mian about their recent analysis to assess for differences in surgical costs and surgery length based on type of EK, use of preloaded grafts, and performance of simultaneous cataract surgery with EK from their Ophthalmology article “Cost Drivers of Endothelial Keratoplasty: A Time-Driven Activity-Based Costing Analysis.” Cost Drivers of Endothelial Keratoplasty. Goldstein, Jenna K. et al. Ophthalmology, Volume 130, Issue 10, 1073 – 1079. Sign up for the next Ophthalmology Journal Virtual Club on March 6, 2024, at https://store.aao.org/ophthalmology-virtual-journal-club.html

The Primary Tube Versus Trabeculectomy Study is a multicenter randomized clinical trial comparing the safety and efficacy of tube shunt surgery and trabeculectomy with mitomycin C in eyes without previous ocular surgery. Dr. Lori Provencher sits down with authors Dr. Sara J. Coulon and Dr. Steven J. Gedde to discuss the results of this trial from their Ophthalmology Glaucoma article, “Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy Study.” Outcomes of Glaucoma Reoperations in the Primary Tube Versus Trabeculectomy Study. Coulon, Sara J.Gedde, Steven J. et al. Ophthalmology Glaucoma, Volume 6, Issue 4, 422 – 431.

Myelin oligodendrocyte glycoprotein-related optic neuritis is typically associated with good visual outcome in most patients, but poor outcomes are reported in 15% to 36.8% of patients. Dr. Drew Carey sits down with Dr. Edward Margolin to discuss the possible factors associated with poor outcomes, from his Ophthalmology article, “Predictors of Poor Visual Outcome in MOG-related Optic Neuritis.” Predictors of Poor Visual Outcome in Myelin Oligodendrocyte Glycoprotein-Related Optic Neuritis. Handzic, Armin et al. Ophthalmology, Volume 130, Issue 9, 993 - 995

Recorded live at AAO 2023 and we’re myth busting common ophthalmologic misconceptions of the anterior segment. Drs. Drew Carey and Matt Feng interview Dr. Todd Margolis on his recent Ophthalmology editorial, “Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology.” He shares bonus myths not in the editorial, and takes questions from the audience. (Producer’s note: Please excuse the audio quality. This episode was recorded on the convention center floor using an iPhone.) Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Margolis, Todd P. & Galor, Anat. Ophthalmology, Volume 130, Issue 8, 783 – 785.

One-third of US ophthalmologists left at least one practice from 2014-2021. What are the factors behind this high turnover rate, how does this affect patient care, and what can be done to stabilize the workforce? Dr. Rajesh Rao interviews Dr. Ravi Parikh about his Ophthalmology article, “Ophthalmologist Turnover in the United States: Analysis of Workforce Changes from 2014 through 2021.” Ophthalmologist Turnover in the United States. Patel, Prem N. et al. Ophthalmology, Volume 130, Issue 9, 973 – 981.

What treatments are effective for uveitic macular edema? Drs. Nisha R. Acharya and Douglas A. Jabs of the MUST Research Group discuss with Dr. Edmund Tsui the landmark findings of the MERIT Trial in their recent Ophthalmology article, “Intravitreal Therapy for Uveitic Macular Edema—Ranibizumab versus Methotrexate versus the Dexamethasone Implant.” Intravitreal Therapy for Uveitic Macular Edema—Ranibizumab versus Methotrexate versus the Dexamethasone Implant. Acharya, Nisha R. et al. Ophthalmology, Volume 130, Issue 9, 914 - 923

News broke in early 2023 of several deaths related to use of contaminated over-the-counter artificial tear products resulting in FDA and CDC warnings and a product recall. Dr. Matt Feng reviews what transpired and discusses lessons learned with Dr. Gary Novack, author of the Ophthalmology editorial, “Infections from Over-The-Counter Artificial Tears: Implications for Patients and Clinicians.” Infections from Over-the-Counter Artificial Tears: Implications for Patients and Clinicians. Novack, Gary D. Ophthalmology, Volume 130, Issue 11, 1114 - 1117 Join us in San Francisco at AAO 2023 for a live recording of our podcast on Saturday November 4, 2023, at 3:30pm local time at the Showcase Theater, Booth #5302, in Moscone Center North. Our hosts will interview Dr. Todd Margolis on his recent editorial, Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Use the Adjunct Event Search for ISC10 in the Mobile Meeting Guide for more information.

Cataract surgery is one of the most commonly performed surgeries globally. What are the risk factors for patients developing pseudophakic cystoid macular edema after cataract surgery? Dr. Edmund Tsui sits down with Dr. Ahmed B. Sallam to discuss the findings of his Ophthalmology article, “Risk of Pseudophakic Cystoid Macular Edema in Fellow-Eye Cataract Surgeries: A Multicenter Database Study.” Risk of Pseudophakic Cystoid Macular Edema in Fellow-Eye Cataract Surgeries. Shakarchi, Ahmed F. et al. Ophthalmology, Volume 130, Issue 6, 640 - 645 Join us in San Francisco at AAO 2023 for a live recording of our podcast on Saturday November 4, 2023, at 3:30pm local time at the Showcase Theater, Booth #5302, in Moscone Center North. Our hosts will interview Dr. Todd Margolis on his recent editorial, Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Use the Adjunct Event Search for ISC10 in the Mobile Meeting Guide for more information.

Does multiple sclerosis contribute to the degeneration of the outer retinal layers? Dr. Drew Carey interviews Dr. Imre Lengyel on his recent Ophthalmology Science article, “Reduced Cone Density Is Associated with Multiple Sclerosis.” Reduced Cone Density Is Associated with Multiple Sclerosis. McIlwaine, Gemma et al. Ophthalmology Science, Volume 3, Issue 3, 100308 Sign up for the next Ophthalmology Journal Virtual Club on October 12, 2023, at https://store.aao.org/ophthalmology-virtual-journal-club.html Join us in San Francisco at AAO 2023 for a live recording of our podcast on Saturday November 4, 2023, at 3:30pm local time at the Showcase Theater, Booth #5302, in Moscone Center North. Our hosts will interview Dr. Todd Margolis on his recent editorial, Six Myths of the Anterior Segment: Misunderstandings and Critical Thinking in Ophthalmology. Use the Adjunct Event Search for ISC10 in the Mobile Meeting Guide for more information.

How can we improve the design and reporting of ophthalmic randomized controlled trials? Dr. Edmund Tsui discusses this with Dr. Gui-shuang Ying author of Ophthalmology Science’s “Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials.” Characteristics of Design and Analysis of Ophthalmic Randomized Controlled Trials. Dong, Ruiqi et al. Ophthalmology Science, Volume 3, Issue 2, 100266. Sign up for the next Ophthalmology Journal Virtual Club on October 12, 2023, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Can ChatGPT pass the OKAP exam? Dr. Matt Feng interviews author Dr. Fares Antaki about the implications of using a language model artificial intelligence in ophthalmology from his Ophthalmology Science article, “Evaluating the Performance of ChatGPT in Ophthalmology: An Analysis of Its Successes and Shortcomings” Evaluating the Performance of ChatGPT in Ophthalmology. Antaki, Fares et al. Ophthalmology Science, Volume 3, Issue 4. The American Academy of Ophthalmology requires that authors request and obtain permission to use any Academy content (including, but not limited to, anything published in the Ophthalmology family of journals) prior to inputting into, or using with, AI systems such as large language models. Sign up for the next Ophthalmology Journal Virtual Club on October 12, 2023, at https://store.aao.org/ophthalmology-virtual-journal-club.html

Is an eye stroke (CRAO) the same as a brain stroke? What new treatments are available for eye stroke? Dr. Drew Carey sits down with Drs. Aubrey Gilbert and Robin Vora to discuss their Ophthalmology Retina article, Central Retinal Artery Occlusion: Time to Presentation and Diagnosis.  Central Retinal Artery Occlusion. Shah, Ronak et al. Ophthalmology Retina, Volume 7, Issue 6, 527 - 531 Sign up for the next Ophthalmology Journal Virtual Club on October 12 at https://store.aao.org/ophthalmology-virtual-journal-club.html

Primary angle-closure glaucoma is a leading cause of vision loss, affecting an estimated 20 million people. Dr. Lori Provencher sits down with Dr. Benjamin Xu to discuss the research from his article, “Rates and Patterns of Diagnostic Conversion from Anatomical Narrow Angle to Primary Angle-Closure Glaucoma in the United States.” Rates and Patterns of Diagnostic Conversion from Anatomical Narrow Angle to Primary Angle-Closure Glaucoma in the United States. Yoo, Kristy et al. Ophthalmology Glaucoma, Volume 6, Issue 2, 169 - 176

Dr. Matt Feng interviews Drs. Koji Kitazawa and Shigeru Kinoshita about their research on endothelial cell loss after corneal transplantation from their Ophthalmology Science article, “The Biologic Character of Donor Corneal Endothelial Cells Influences Endothelial Cell Density Post Successful Corneal Transplantation.” The Biologic Character of Donor Corneal Endothelial Cells Influences Endothelial Cell Density Post Successful Corneal Transplantation Kitazawa, Koji et al. Ophthalmology Science, Volume 3, Issue 2, 100239