SciPod

In recent years, rapid advancements in techniques for genetic analysis and manipulation have enhanced our potential to understand and improve crop diversity. An innovative project led by Dr. Pasquale Tripodi of the Italian Council for Agricultural Research and Economics and Dr Sandra Goritschnig of the European Cooperative Programme for Plant Genetic Resources marks a significant advance in the study of lettuce genetics. Their recently published research platforms a highly sophisticated technique to analyse genetic diversity within lettuces called Single Primer Enrichment Technology, or SPET for short. This approach provides a highly detailed view of lettuce genetics and also has significant implications for agricultural resilience and crop selection and breeding.

The development of safe and effective medicines that meet strict regulatory requirements has traditionally involved extensive experimentation, which can be laborious and costly. Incorporating digital processes, which can be used to produce individual pharmaceutical components, may provide a solution to manufacturing challenges by reducing development time, resource requirements, and costs. The Future Continuous Manufacturing and Advanced Crystallisation Hub, a flagship project at CMAC, at the University of Strathclyde, along with collaborators throughout the UK, has investigated the feasibility of using digital models to reduce costs, time and waste for high quality pharmaceutical production.

With a history as rich as its flavour, chocolate in its various forms has been loved by people for over 5000 years. Currently, however, chocolate is facing a serious threat. The improper disposal of cocoa waste products is spreading devastating diseases through cocoa crops across the world. To address this serious problem, Dr Piergiorgio Gentile from Newcastle University and Dr Joel Girón-Hernández from Northumbria University with their collaborators have been exploring new uses for cocoa waste products, to increase sustainability and prevent the spread of crop diseases.

Brazil, Russia, India and China, often known as the BRICs, have seen explosive growth in the past two decades and have asserted themselves as drivers of globalisation. Many scholars have researched the effects of this growth and development, and how these factors have affected domestic labour conditions. But are they asking the right questions? For instance, if developing countries invest in developed economies, will this lead to improved working conditions in the investing developing nation? Dr Patrick Wagner of the University of Konstanz, Germany, and Professor Damian Raess of the Catholic University of Lille, France, have conducted a study investigating whether Brazilian direct investment in Europe leads to improved working conditions back in Brazil.

Our world is facing new and frightening challenges, and political polarization has never been greater. Many see reasoned, respectful discourse as our only path to survival and progress, but attaining the skills and values it requires is not straightforward. Professor Deanna Kuhn of Columbia University has developed a discourse-based curriculum to help the next generation develop the values and the social and critical thinking skills they will need if they are to use tools of discourse to address the complex problems and challenges that await them.

In 18th century Britain, the old tradition of deep bowing and curtseying as a form of greeting slowly evolved into a brief touch of the cap or head (for men), or quick bob of the body (for women). Simultaneously, a new form of urban greeting was emerging: the handshake. How and why did the handshake gain such popularity, becoming our most standard greeting today? This phenomenon is explored in a new essay published in the journal Urban History and authored by Professor Penelope Corfield of London University.

Dr. Christopher Buck, a virologist at the US National Cancer Institute in Bethesda, Maryland, has been working to spread the word about a growing body of scientific literature suggesting that mint and related herbs can help fight Covid infections. In his recent review article, “The Mint Versus Covid Hypothesis,” he makes a case for the idea that decentralized clinical trials could be used to more thoroughly explore this exciting idea.

Since ancient Greek civilization, we have sought to identify what makes some people more effective and persuasive orators than others. Studies have suggested that this might be related to rhythmic patterns in certain speech, but evidence is limited. Dr. Ceccherini-Nelli of the University of Alberta conducted a study with his colleagues to explore this. They looked at the patterns present in political speeches and conducted experiments to determine their effects.

AI appears all-powerful when playing sophisticated games such as Chess and Go against human opponents. Moreover, recent developments in AI have allowed it to summarize bodies of complex text, generate images and even video. These developments come with warnings that AI could replace many jobs, undermine democratic elections or even pose a threat to the existence of humanity. However, AI is largely based on observing and learning patterns; so, what happens when there are no patterns? Professor Steven Brams of New York University and colleagues have analyzed the potential of beating AI when playing a deceptively simple game called Catch-Up, simply by making random moves.

During brain development, anomalies may arise which lead to serious conditions such as epilepsy, triggering seizures and requiring lifelong monitoring and medication. However, the underlying causes and the way in which these defects occur are not completely understood. Dr Katty (Jing-Qiong) Kang and colleagues at Vanderbilt University Medical Centre in the USA have conducted extensive research into the molecular mechanisms associated with developmental brain disorders, with a focus on genetic epilepsy. They propose novel therapeutic targets to effectively manage symptoms and improve clinical outcomes by targeting the root cause.

Shallow coastal waters are home to a unique and important plant – the seagrasses. Seagrasses, defined as underwater flowering plants, form vast meadows within shallow coastal waters across almost all continents. Seagrass meadows are one of the most significant ecosystems on the planet, and our future depends on them. Seagrass is vital for biodiversity, supports global fisheries, and is indispensable for tackling climate change. Despite the value of seagrass meadows, efforts to conserve them are falling short. Through their research, Riccardo Losciale and his team from James Cook University in Australia aim to identify and overcome the barriers to seagrass conservation.

As a medical specialty, anesthesiology has made remarkable progress to deliver patient safety at an incredibly high level, while administering drugs that could potentially be very dangerous at a slightly increased dose. However, just like the case of Icarus, a character in Greek mythology who flew too close to the sun before plummeting back to Earth, success can carry the seeds of failure. The impressive progress towards patient safety could conceivably lead to the extinction of anesthesiology as a specialty. In the context of cutting costs and an environment where the return-on-investment for anesthesiologists is not always clear, there may be a temptation to replace anesthesiologists with other professionals, such as specialized sedation nurses, or with new technologies.

The war in Ukraine has tested the resilience and unity of the European Union in unprecedented ways. As with some past European crises, EU member states have shown a willingness to unify and cooperate. However, unlike during other crises, this hasn’t resulted in strengthened EU regulatory or fiscal powers. In recent research, Professor Tanja Börzel at Freie Universität Berlin explores why this is the case.

Individuals with dyslexia encounter difficulties in learning to read, despite possessing a normal level of intelligence and having access to qualified teachers and educational materials. However, the causes of dyslexia remain disputed. One suggestion is that dyslexia may be related to stress, either experienced by the afflicted individual at a young age, or through inheriting stress-related biological changes from their parents. Dr John Kershner, a neuropsychologist at the University of Toronto, has conducted extensive research on this alternative hypothesis and provides compelling evidence to support this emerging concept.

Dr. P. R. Raghavan, CEO and Chairman of Nanorx Inc., developed Metadichol, a nutritional supplement that has shown potential in treating a range of health issues. Dr. Raghavan suggests that the supplement may help to stave off illnesses such as diabetes and antibiotic-resistant infections.

Anesthesia in the US is currently delivered through a team-based approach, with physician anesthesiologists supervising certified registered nurse anesthetists. However, in over 20 states, there is no requirement for nurse anesthetists to be supervised by anesthesiologists, allowing them to work independently. This has resulted in a bitter turf war over the rights and responsibilities of physicians and advanced practice nurses working in this discipline to provide patient care, paving the way for daily acrimony and a toxic working environment. The mindset behind this adversarial approach can be compared with a “finite game”, where there are clear winners and losers. Aiming to challenge this dysfunctional tribalism, Dr. Matthew Sherrer from the University of Alabama Birmingham and colleagues have drawn on an alternative mindset: the infinite game.

Artificial intelligence – or AI – is receiving increasing attention for its rapid development and potential to change society. Researchers are working hard to develop its capabilities, while regulators are racing to ensure it is managed and governed properly. But what do we mean by AI, and how can we define such a complex term? In a recent paper, Professor Pei Wang at Temple University argues that the lack of an agreed definition makes it difficult for policymakers to assess what AI will be capable of in the near future, or even which kinds of AI are desirable. To combat this, he discusses what makes a robust definition, and suggests his own.

Tuberculosis – or TB – is a global health threat, with 10 million new cases annually. Diagnosing TB can be a challenge, as there is a lack of rapid, point-of-care diagnostic tests. It can also be difficult to distinguish between TB and other inflammatory diseases, such as Sarcoidosis. One option may be to identify antibodies in patient samples that can reveal the presence of TB. However, current antibody tests for TB lack accuracy. Professor Lobelia Samavati and colleagues at the Wanye State University School of Medicine in Michigan are tackling this challenge to cast light on the immune signature of these diseases. Their aim is to develop new diagnostic techniques for TB and Sarcoidosis.

Businesses today exist in a changing world, which brings both opportunities for growth and increasingly complex challenges. To survive and thrive, organisations need a robust understanding of HR management. In their research, Professor Xiaobei Li and her colleagues at various universities, including University of New South Wales, Arizona State University and Peking University, recently explored how organisations can motivate their staff to ensure high-quality performance.

India has seen impressive economic and institutional growth in recent years, but the country isn’t yet meeting its full potential. In a world that is increasingly volatile and uncertain, how can India overcome its challenges and ensure resilience into the future? In her recent work, Professor Uma Lele explores various ways that India can achieve this.